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Paper title Feasibility and safety of intraoperative BOLD MRI cerebrovascular reactivity to evaluate extracranial-to-intracranial bypass efficacy
Paper code P40
  1. Giovanni Muscas Universitätsspital Zürich Speaker
  2. Bas van Niftrik Universitätsspital Zürich
  3. Marco Piccirelli Universitätsspital Zürich
  4. Jan Karl Burkhardt Universitätsspital Zürich
  5. Martina Sebök Universitätsspital Zürich
  6. Athina Pangalu Universitätsspital Zürich
  7. Antonios Valavanis University Hospital Zurich
  8. Oliver Bozinov Kantonsspital St. Gallen
  9. Luca Regli UniversitätsSpital & Universität Zürich
  10. Jorn Fierstra Universitätsspital Zürich
Form of presentation Poster
  • Joint SSNR | SSNS
Abstract text Aims: Blood Oxygenation-Level dependent Magnetic Resonance Imaging (BOLD MRI) sequences help to investigate cerebrovascular reactivity (CVR) to predict stroke risk in patients affected from chronic cerebrovascular steno-occlusive diseases.
We aimed to conduct a preliminary study to investigate the feasibility and safety of intraoperative BOLD MRI to assess CVR in extracranial-to-intracranial bypass (EC-IC) procedures.
Methods: Eight patients operated with EC-IC bypass underwent an additional intra-operative MR scan with BOLD sequences to assess CVR with breath-holding based techniques after the anastomosis.
Results: None of the patients showed post-operative complications or radiological alterations related to prolonged anesthesia time. One patient presented with a hyperperfusion syndrome postoperatively unrelated to the intra-operative MRI. CVR maps were obtained in all subjects showing qualitative variations.
Conclusion: Intra-operative BOLD MRI sequence acquisition is a safe option for patients undergoing surgery for EC-IC bypass. This technique might offer important and immediate information on the success and efficacy of a bypass.