Paper title | Comparison of New-Generation Double-Layer Micromesh Carotid Stent-System versus Carotid Self-expanding Hybrid Stent System in Symptomatic Carotid Artery Stenosis |
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Paper code | P61 |
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Form of presentation | Poster |
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Abstract text |
Objective: Carotid artery stenosis is a relevant cause of ischemic stroke. Carotid artery stenting is an emerging alternative treatment option to surgical carotid endarterectomy. Several carotid stent-systems with different stent designs are available. CASPER (MicroVention, Inc., USA) – a double-layer micromesh carotid stent-system designed to prevent peri-procedural embolic release – belongs to the latest generation of carotid stent system. The aim of this study was to assess efficacy and safety of CASPER compared to a carotid self-expending hybrid stent system (Invatec Cristallo Ideal, Medtronic, USA) (Cristallo) in symptomatic carotid artery stenosis (sCS). Method: A single-center, open-label, retrospective cohort study of 57 consecutive patients with proven sCS between 01/2014–08/2017 executed at a tertiary stroke center in Switzerland. Outcome measures were i) good clinical outcome at 90 days (mRS 0-2), ii) peri-procedural complications and ischemic events iii) re-occlusion rate and iiii) mortality within 30 days. Results: 22 patients (23% women, median age 75 years (interquartile range (IQR) 71-80) were treated with CASPER, 35 patients (29% women, median age 71 years (IQR 63-76) years) with Cristallo. In both groups, pre-treatment carotid stenosis had similar median NASCET score of 80%. Successful deployment was achieved in all cases without technical failure and similar re-occlusion rates and mortality rate within 30 days. Clinical outcome was similarly beneficial in both groups. In the Cristallo group peri-procedural ischemic event was insignificantly higher (3 vs 0; p=0.16). Conclusion: CASPER and Cristallo demonstrate to be similarly effective and safe in symptomatic carotid artery stenosis. |