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Paper title Long-term outcome after resection of meningiomas involving the superior sagittal sinus
Paper code P13
Authors
  1. Donato D'Alonzo Kantonsspital Aarau Speaker
  2. Fabio Strange Kantonsspital Aarau
  3. Jaqueline Lattmann Kantonsspital Aarau
  4. Gilles Dutilh Universitätsspital Basel
  5. Serge Marbacher Kantonsspital Aarau
  6. Javier Fandino Kantonsspital Aarau
  7. Lucia Schwyzer Kantonsspital Aarau
Form of presentation Poster
Topics
  • SSNS-Neurosurgery
Abstract text Aim
The role of radical resection and combined therapies of parasagittal meningiomas invading the superior sagittal sinus (SSS) on tumor control and long-term outcome are still controversial. Recent studies reported a unfavorable outcome in terms of morbidity and mortality after radical surgery compared with a partial tumor removal. The aim of this study was the evaluation of the short-term and long-term outcome in patients undergoing surgical treatment with or without resection of the SSS.
Methods
We retrospectively analyzed the data of 45 patients who underwent surgery for parasagittal meningioma between 2007 and 2014 in our institution. Demographic characteristics, clinical and radiological findings including volume of the tumor, resection Simpson grade, histological classification and outcome by measuring degree of disability (modified Rankin Scale (mRS) and extended Glasgow Outcome Scale (eGOS), were documented. Of interest were the outcomes in patients with tumor recurrences as well as the correlation of initial tumor size and treatment decision.
Result
The mean age was 59.8 years (19-85 y); 18 patients male (40%); 27 female (60%). The initial mean tumor volume was 45.2 cm3 (2 – 201 cm3). A radical resection of the tumor was achieved in 16 cases (36%), 8 (18%) cases underwent additional SSS resection. A partial tumor resection was performed in 29 cases (64%) without SSS resection. The mean postoperative residual tumor volume was 1.7 cm3 (0.26 – 11.9 cm3). Histology revealed WHO grade I in 38 cases (84%) and seven cases were atypical (WHO grade II, 16%). Two patients died during their hospital stay (4%) due to surgical complications. 6 (14%) out of 43 cases were lost to follow-up, leaving 37 patients with a mean follow-up time of 53.6 months. The preoperative mRS and eGOS in 43 patients changed at hospital discharge from 1 to 2 and from 7 to 5, respectively. However, overall the long-term outcome showed an excellent recovery in all patients, with a mRS of 0 or 1 and eGOS 8 or 7 respectively. During follow-up, 17 patients experienced a tumor recurrence and 6 patients underwent reoperation. A total of 6 patients underwent radiosugery.
Conclusions
Favorable clinical outcome and long-term tumor control after partial resection of parasagittal meningioma involving the SSS were documented in this series. This treatment strategy seems not inferior to radical surgery and confirms previous reported studies.