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Paper title Intracranial Meningeal Hemangiopericytomas: An Analysis of factors affecting outcome from multimodality treatment of 39 Cases.
Paper code P01
Authors
  1. Amandeep Kumar All India Institute of Medical Sciences, New Delhi Speaker
  2. Manmohan Singh All India Institute of Medical Sciences, New Delhi
  3. Deepak Agrawal All India Institute of Medical Sciences, New Delhi
  4. Pankaj Singh All India Institute of Medical Sciences, New Delhi
  5. Poodipedi Chandra All India Institute of Medical Sciences, New Delhi
  6. Shashank Kale All India Institute of Medical Sciences, New Delhi
Form of presentation Poster
Topics
  • SSNS-Neurosurgery
Abstract text Aim: To retrospectively evaluate outcome of patients with intracranial menin-geal hemangiopericytomas (MHPCs) & to analyse various factors for recur-rence and survival in these patients.
Materials & Methods:
We retrospectively reviewed the clinical data of 39 patients undergoing micro-surgical resection for MHPCs at our institute from 2009 to 2015.
Results:
GTE was achieved in 27 (69.2%) patients while 12 (30.8%) underwent STE. Twenty five patients received radiotherapy (Conventional RT-15; GKT-10). Twenty one patients had low grade while 18 had anaplastic variant. Twenty pa-tients (51.3%) developed recurrences. Average recurrence free survival (RFS) was 56 months (range:12-180 months). Eight patients (20.5%) died during study period. The average overall survival (OS) was 77.2 months (range: 36-192 months). Two patients (5.1%) developed systemic metastases during fol-lowup. Patient age was not found to affect RF or OS. GTE was associated with prolonged RFS & OS but the impact was not statistically significant (p values-0.160 & 0.414 respectively). Low tumor grade was associated with statistically significant longer RFS as well as OS (p values-0.049 & 0.013 respectively). Addition of adjuvant RT was associated with statistically significant prolonga-tion of RFS (p value-0.016) however, it was not associated with statistically significant overall survival benefits (p value-0.758).
Conclusions:
Our study suggests that extent of excision, low tumor grade & addition of adju-vant RT have a positive impact on both RFS & OS, however, low grade & ad-juvant RT were the only factors associated with statistically significant prolon-gation of RFS & only tumor grade was associated with statistically significant overall survival benefits.